That pimp masquerading as a scientist? Yes, he's certainly the most explicitly evil character, but I think that Stadler's evil is greater: he lived by reason and abandoned it for expediency, where the other villains never lived a rational life
kismet_113
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My vote would be Dr. Stadler; he was never ignorant of reality. All of the nominees refused to think, but Stadler stared reason in the face and failed it.